The general rule of thumb for baking lasagna is to cook it in a preheated oven at 350-375°F (175-190°C) for about 30-40 minutes. But, let's be real, that's like asking how long it takes to fall in love - it's all about the chemistry, baby! The key is to check on it every 10-15 minutes to ensure it's not getting too crispy on the outside or too soggy on the inside.
Now, I know what you're thinking: "What about the size of the lasagna?" Well, that's a great question! If you're making a smaller lasagna, you'll want to check on it after 20-25 minutes, while a larger one might take up to 50 minutes to cook through. Just remember, it's all about the layers, baby - you want them to be tender, not mushy!